FTA:<p>"To Walter’s dismay, some are buying ISRIB online and ingesting it, long before it’s been extensively tested...<p>Some outside scientists remain skeptical. They warn that interfering with vital cellular mechanisms, as ISRIB seems to do, could lead to a host of dangerous side effects. They caution that it will be years, or possibly decades, before it’s ready for testing in humans."<p>Cause, meet effect.
How does this now-patented "ISRIB" molecule compare to Leonard Guarente's research[1][2] on nicotinamide riboside and pterostilbene supplementation?<p>[1]: <a href="http://nymag.com/scienceofus/2016/08/is-elysium-healths-basis-the-fountain-of-youth.html" rel="nofollow">http://nymag.com/scienceofus/2016/08/is-elysium-healths-basi...</a><p>[2]: <a href="https://news.ycombinator.com/item?id=12345526" rel="nofollow">https://news.ycombinator.com/item?id=12345526</a>
An interesting new approach. Let's wait for the studies to follow.<p>He is mistaken about "nothing" in case of brain trauma. Racetams have been shown to be mildly effective.
The article's title on statnews.com bugs me, I admit I have not investigated this case, but...<p>I suspect it wasn't that graying old man that discovered that molecule, but that man's brilliant but underpaid post-doc that discovered that molecule.