Looks like they're trying on sheep earlier this year.<p><a href="http://www.biotechniques.com/news/Breaking-Boundaries-Ultrasound-Treatments-for-Alzheimers-Disease/biotechniques-363211.html#.WB4iqdUrKVM" rel="nofollow">http://www.biotechniques.com/news/Breaking-Boundaries-Ultras...</a><p>> Leinenga is also trying to apply the technique to sheep since their skulls are similar in thickness to human skulls. The larger sheep brain is also closer in size and shape to human brains as well. Having a similar model is important for developing ultrasound technology, because the physics can differ in a mouse versus a human due to the difficulty of transmitting through a thicker human skull.
Research appears to be ongoing<p><a href="http://www.forbes.com/sites/oracle/2016/11/03/on-path-to-alzheimers-cure-australian-team-analyzes-petabytes-of-data" rel="nofollow">http://www.forbes.com/sites/oracle/2016/11/03/on-path-to-alz...</a>
Apparently they still haven't been able to translate the treatment to work on humans.<p>Also, it hasn't yet been proven that the treatment itself is completely safe for the brain.
When I see stuff like this I have to say I am amazed at how precise some drugs are.<p>Somewhat related I was watching a video about protein motors and how they work. They are small structures that walk on microtubules (as mentioned in the Alzheimer's article) inside cells. There are many types but some walk using hinged protein feet.<p>The narrator explained how his team invented a drug that helped to make one step in that process better. They made the hinge part of the foot work normally giving it more strength. It was a single phosphate molecule added to this step.<p>It was incredible to think one small part of a protein motor the "ankle" part of the foot of that one protein motor on a microtubule inside a single cell had some help.<p>I explained it horribly here is the video <a href="https://youtu.be/9RUHJhskW00?t=1946" rel="nofollow">https://youtu.be/9RUHJhskW00?t=1946</a><p>edit: phosphate not sulphur
One of the more intriguing things in this work is that they used a physical process. This makes it much more likely to work across in other animals/humans.