My current day job involves doing the tech behind a series of dementia related online courses.<p>Awesomely, we just kicked off the latest running of our Preventing Dementia MOOC:<p><a href="https://mooc.utas.edu.au/courses/preventing-dementia-2017-03" rel="nofollow">https://mooc.utas.edu.au/courses/preventing-dementia-2017-03</a><p>I emailed this link to our academic team as I'm sure they'll get bombarded with people asking why they should make changes to their life style if there is a magical cure just around the corner....
<a href="https://www.gwern.net/Nicotine" rel="nofollow">https://www.gwern.net/Nicotine</a> suggests we already have a drug that works fairly well for some diseases.
New studies indicate that sleep is an important factor in cleaning up protein junk built up in the brain during wakeful hours. I wonder if the "real" impact of trazedone is the improvement in sleep quality and therefore by extension an effective maintainer of neurological physiology.
DBM being <a href="https://en.m.wikipedia.org/wiki/Dibenzoylmethane" rel="nofollow">https://en.m.wikipedia.org/wiki/Dibenzoylmethane</a><p>I'm going to talk to my family whether we should gice this (and trazedone) to my dad
Seems to me it would be just straightforward to get a list of people taking trazodone for long periods and measure their rates of neurodegeneration versus the general population versus those taking ssris.
This is great, but if I read the study correctly, it's only been tested in mice for now. So I wouldn't get my hopes too high for now (I'd estimate the chances of success at 5% or less at this point).