Nothing has ever done me more good than this combination. My biggest success in work at my current company, a big API-first platform for insurance comparison was built from scratch in 2 weeks time, spent locked inside my apartment, coffee machine running 24/7, a 100mg cookie in the morning and a joint every 2 hours. No one knows.
I am a total layman, so could somebody explain the significance of this study? Obviously those substances alter the brain chemistry, that is not surprising, I think. How are those changes significant? Is there cause for concern?
Please stop posting these pre-clinical studies on rats and mice! No one should ever be taking anything away from these sorts of studies for human health.
Maybe more informative is <a href="https://www.annualreviews.org/doi/full/10.1146/annurev-nutr-071816-064941" rel="nofollow">https://www.annualreviews.org/doi/full/10.1146/annurev-nutr-...</a><p>Maybe paywalled so I'll emphasize the last sentence of the abstract: "Given the spectrum of conditions studied and the robustness of many of the results, these findings indicate that coffee can be part of a healthful diet."
paper affiliation <a href="https://en.wikipedia.org/wiki/Babcock_University" rel="nofollow">https://en.wikipedia.org/wiki/Babcock_University</a>
Mac Lethal made a song about it:<p><a href="https://youtu.be/DTY3GQPXU7A" rel="nofollow">https://youtu.be/DTY3GQPXU7A</a>
Looks like a crap article in a crap journal. In the abstract they refer to cannabis as a stimulant, which seems quite incorrect. Also the results are unsurprising and not very exciting.