For context: the blog post itself is sort of rambling and a bit hard to understand, but the email back and forth below the post is pretty interesting and features some of the most prominent people in the biotech startup world.<p>Steve Holtzman (the author) is a very successful serial biotech entrepreneur. Jeff Tong is a venture partner at Third Rock, sort of the Andreesen Horowitz of the biotech world. Mark Levin is a cofounder of Third Rock. His reply is really good. John Maragone is the CEO of Alnylam, one of the early RNAi companies, and chair of the biotech industry trade group