No explanation as to the cause of the shortcoming. Do drug companies just hate money?<p>Madehow has a decent article on the history of insulin synthesis [1]. I don’t see any natural bottlenecks that would interfere with scaling the process.<p>1. <a href="http://www.madehow.com/Volume-7/Insulin.html" rel="nofollow">http://www.madehow.com/Volume-7/Insulin.html</a>
Type 2 diabetes can be reversed through diet. The evidence comes from medical practitioners and scientists, not from quacks making outlandish claims (although they exist too).<p>Some links:<p><i>The Diabetes Code by Jason Fung</i>: This is a best-selling book by a Canadian Nephrologist (care and treatment of kidney disease) that explains type 2 diabetes in detail and recommends diabetics switch to a low-carb diet.<p><i>Counterweight Plus low-calorie diet plan</i>: This diet was run as part of a scientific trial and showed promising results for obese patients with type 2 diabetes. Nearly half of the 300 patients in the trial reversed their diabetes. Note: the diet was run under the supervision of medical professionals and is not suitable for everyone:
<a href="https://www.nhs.uk/news/diabetes/radical-low-calorie-diet-may-help-reverse-type-2-diabetes/" rel="nofollow">https://www.nhs.uk/news/diabetes/radical-low-calorie-diet-ma...</a><p><i>The Truth about Carbs</i>: this is a BBC documentary from earlier this year which is unfortunately no longer available to watch on the BBC website. It featured NHS doctors who ran a two-week low-carb diet plan with type 2 diabetic patients. All patients reported improvements to their health, but the most impressive result was a patient with type 2 diabetes for 17 years who was now in part-remission.<p>Here is a thorough write-up of the programme:
<a href="https://www.diabetes.co.uk/in-depth/truth-about-carbs-bbc-1-review/" rel="nofollow">https://www.diabetes.co.uk/in-depth/truth-about-carbs-bbc-1-...</a><p>A clip from the programme: <a href="https://www.youtube.com/watch?v=eKQWFJmCWZE" rel="nofollow">https://www.youtube.com/watch?v=eKQWFJmCWZE</a><p>10 things you may not know about carbs: <a href="http://www.bbc.co.uk/programmes/articles/4DfZMpv7BYJ3kGXdHxdxkKp/10-things-you-may-not-know-about-carbs" rel="nofollow">http://www.bbc.co.uk/programmes/articles/4DfZMpv7BYJ3kGXdHxd...</a><p>Just to re-iterate, the examples above all refer to types 2 diabetes, not type 1 diabetes.
Wonder why they picked 2030. I _might_ have read a 3-year forecast since they are sometimes correct. But any forecast involving social processes that is beyond 5 years is almost always wrong.
Virta Health is a sf startup with meaningful results reversing T2 diabetes. If you’re interested in this topic they are a compelling counterpoint to this study.
How about we stop masking the problem of insulin resistance by pumping type 2 diabetics with insulin?<p>Why don’t we start telling diabetics the truth — your diet is broken and needs to be fixed; avoid most carbs, do strength training.<p>We don’t need more insulin to shove the massive onslaught of blood sugar from your crappy diet into your cells (which are telling you they’ve had enough, AKA insulin resistance), we need more honesty.<p>The healthcare industry is morally and intellectually bankrupt. All the honest people who got into it trying to make a real difference don’t stand a chance, the truth doesn’t survive for an instant in this corrupt industry more focused on how much they can get out of insurance companies than treating patients.