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ReSeq: Repurposing HiSeq DNA Sequencers

59 pointsby kasbahover 6 years ago

6 comments

snarfyover 6 years ago
Mikeselectricstuff has some teardown videos of DNA sequencers. Interesting stuff.<p><a href="https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=XaumUp4GpCw" rel="nofollow">https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=XaumUp4GpCw</a>
kasbahover 6 years ago
I am part of this project but just about to board a 2 hour flight. If you have any questions, feel free to post below and I will answer them later.
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astazangastaover 6 years ago
What about reagents? The sequencers themselves are expensive, but library kits cost a lot of money, as do the reagents for running a flow cell. Even if I can get a sequencer for free, if I still have to pay through the nose for reagents it&#x27;s no good. Especially as these sequencers become obsolete and people stop MAKING the relevant reagents, and their cost goes higher and higher.
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adenadelover 6 years ago
Here&#x27;s another series of posts where they tear down one of the original Illumina sequencers (the Genome Analyzer).<p><a href="https:&#x2F;&#x2F;blogs.swarthmore.edu&#x2F;Illumina+GAIIx+Teardown&#x2F;" rel="nofollow">https:&#x2F;&#x2F;blogs.swarthmore.edu&#x2F;Illumina+GAIIx+Teardown&#x2F;</a>
skosuriover 6 years ago
Ooh. I got a HiSeq 2000 for a six pack of beer. Can’t wait to try to hack it!
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hyperbovineover 6 years ago
Boy, do I feel old. HiSeq 2500 was a gold-standard, $750k machine when I was starting grad school. Which was not that long ago, or so I thought.