Also of note: asymptomatic carriers like Typhoid Mary: <a href="https://en.m.wikipedia.org/wiki/Mary_Mallon" rel="nofollow">https://en.m.wikipedia.org/wiki/Mary_Mallon</a>
I saw a thing about Typhoid Mary a couple years back. I hadn't realized that she was contagious for most of her life.<p>She was a cook, and they told her she should never handle food for others again. They later caught her working with food, and she went (back) into mandatory quarantine for the last 23 years of her life. She lived to 69, having spent a little over half of her adult life imprisoned.<p>They had a theory that removing her gallbladder would cure her, but she refused.
Fascinating how these events are traced and studied. Most compelling one for HIV traced to 1959 in Congo - <a href="https://en.wikipedia.org/wiki/History_of_HIV/AIDS#History_of_spread" rel="nofollow">https://en.wikipedia.org/wiki/History_of_HIV/AIDS#History_of...</a>