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Ask HN: Any clinical trials / RWE companies studying HCQ for Covid-19?

3 pointsby aaavl2821about 5 years ago
Some of the most promising potential treatments for COVID-19 are chloroquine (CQ, a malaria medicine) and hydroxychloroquine (HCQ), a less toxic version of choloroquine that is used for malaria as well as lupus and arthritis. Here is the current prescribing info for CQ [0] and HCQ [1]<p>These drugs are already approved. There is emerging evidence that these drugs are promising (see below refs). But the evidence is VERY preliminary. WHO is organizing a much larger study to test these and other drugs [2]. Other companies are also ramping up studies. But it will take time to generate the data<p>Because HCQ is fairly non-toxic, it might make sense for health care providers treating COVID-19 patients to take this as a preventative measure. They are already low on protective equipment and at high risk<p>But we need to study whether the drugs actually work. Are there companies that can help run &quot;virtual&quot; studies -- where HCPs can take the drug, record their doses taken, health characteristics, and clinical outcomes? This would balance need for data collection with need for immediate tx for HCPs<p>[0] https:&#x2F;&#x2F;www.accessdata.fda.gov&#x2F;drugsatfda_docs&#x2F;label&#x2F;2017&#x2F;006002s044lbl.pdf<p>[1] https:&#x2F;&#x2F;www.accessdata.fda.gov&#x2F;drugsatfda_docs&#x2F;label&#x2F;2017&#x2F;009768s037s045s047lbl.pdf<p>[2] https:&#x2F;&#x2F;www.statnews.com&#x2F;2020&#x2F;03&#x2F;18&#x2F;who-to-launch-multinational-trial-to-jumpstart-search-for-coronavirus-drugs&#x2F;<p>https:&#x2F;&#x2F;www.arabnews.com&#x2F;node&#x2F;1643141&#x2F;world<p>https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;s41421-020-0156-0<p>https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pubmed&#x2F;32150618<p>https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pubmed&#x2F;32164085

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