An illustrative link: <a href="https://infoproc.blogspot.com/2017/03/everything-is-heritable.html" rel="nofollow">https://infoproc.blogspot.com/2017/03/everything-is-heritabl...</a> (A short post with a nice chart, contains a further link to a proper paper.)<p>Regarding the pessimism of genetic pre-determination and this congenital disadvantage: I think the real progress of society is how it learns to make lives of <i>different</i> people productive and satisfying. E.g. nerdy types had it hard in, say, 19th century Europe, but now they have a great and important niche in engineering. Same happened to many more predispositions of people that now lead to something interesting instead of pure misery.<p>I think this process is not going to stop.
So how will society adapt when specific genetic variants inevitably are tied to predisposition for intelligence and behavior?<p>ADHD, autism, BPD, as listed in the article, are not specific conditions, but rather represent a range of behavioral and intellectual tendencies that are better described as clusters in high dimensional personality space. If there are already 300 genes mapped which influence this handful of conditions, that implies that we already know of specific genes which effectively influence behavior by shifting psychology around these clusters.<p>And since genes are heritable, this has consequences for groups of people and their interactions in greater society. This may be an unpleasant question but if research proceeds in this field it is one that will have to be answered.