As pointed out already, there is a thriving startup scene in the Boston area. I think some of the "knocks" Vivek Wadhwa makes about SV being "more failure-cherishing, more risk-taking, better capitalised" are either not good things or not really true. First off more failure-cherishing winds up meaning that more VC money is essentially wasted by people building things that have no business model or aren't even remotely useful. Failure isn't always a bad thing, but I wouldn't pride myself or the community I'm part of on being happy to fail. Second more risk-taking means the same enourmous sums of VC money wasted and it also means, in my opinion, that people are willing to overlook or can't see glaring issues with proposed businesses and invest anyway. Lastly, there are a large number of VCs here in the Boston area and I don't see that changing anytime soon.<p>Three other points. One, if Boston were so bad for the startup scene or tech in general then why is basically every big player here? Microsoft, google, vmware, akamai, IBM, cisco, juniper, emc, netapp, the list goes on. These companies aren't here because there isn't any talent or it's a bad place to be. Two, many of the companies on the list are companies that have been around for a while and are thriving, profitable and growing on their own. Last, and as has been pointed out, there is a <i>huge</i> biotech scene here, as well as a large amount of government/defense research related work (irobot, raytheon, mit, boston dynamics).