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Human body-on-chip platform could speed up drug testing

84 pointsby trottabout 5 years ago

5 comments

hprotagonistabout 5 years ago
If you can really, truly get liver-on-a-chip to work, it&#x27;s going to positively change drug testing forever and will be the first huge win for tissue engineering.<p>You can throw away animal models for tox screens forever, and that&#x27;s great news. It will save vast amount of time and money. By using a much better proxy model for humans (slices aren&#x27;t organs, they have different rheological characteristics and morphology, but they&#x27;re a damn sight better than mice), you&#x27;ll wash out candidates earlier and faster, and hopefully enrich the pipeline.<p>Slowly but surely, and it&#x27;s good to see steps in this direction.
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echelonabout 5 years ago
We need to clone decephalized humans and livestock.<p>With thousands of brainless bodies kept alive on life support, you have test subjects for a limitless number of experiments that would have never been possible before. You also create a never-ending O negative blood supply and organ harvesting program.<p>It the case of decephalized animals, you also get cruelty free meat. And that&#x27;s how you bootstrap the program and port it to the human model.<p>There would be a lot of political pressure, but this would be a space-age jump in supporting fundamental biological research, supplying renewable body parts and tissues, and keeping us healthy and young.<p>We need to do it.<p>If I ever get Elon Musk money and power, I&#x27;m doing this instead of rockets.
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dvtabout 5 years ago
Does anyone have a layman-accessible explanation for how exactly this works? My last biology class was freshman year of college, but I find the &quot;body-on-chip&quot; startups incredibly interesting. I take it this is different than &quot;growing&quot; organs via stem cells?
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TravisSc6ttabout 5 years ago
So they&#x27;re basically trying to simulate humans? What a world we live in
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econconabout 5 years ago
I&#x27;ve heard nearly any implant you put inside body has negative impact and this is also true for titanium implants which is seemingly inert and harmless metal.<p>How many people their body with some industrial chip, I&#x27;ll never use anything like this unless my life depends on it.
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