Hey HN! I wanted to find not-so-popular companies working on hard tech, long term problems, broadly falling into, but not relegated to, nuclear and clean energy, genetics, robotics, high performance computing, self driving cars.<p>I think there are quite a few companies like this in various countries, away from SF PR that we don't know about.
The Broad Institute:<p><a href="https://www.broadinstitute.org/about-us" rel="nofollow">https://www.broadinstitute.org/about-us</a><p><a href="https://broadinstitute.wd1.myworkdayjobs.com/broad_institute" rel="nofollow">https://broadinstitute.wd1.myworkdayjobs.com/broad_institute</a><p>I work there. My group builds scalable tools for genomic data analysis:<p><a href="https://hail.is" rel="nofollow">https://hail.is</a><p>We're about to post two job reqs, for an SRE and front-end/design position. Email in my profile. Get in touch if you're interested.<p>gnomAD is the largest public dataset of human genetic variation:<p><a href="https://gnomad.broadinstitute.org/" rel="nofollow">https://gnomad.broadinstitute.org/</a><p>They recently a 7 paper collection in Nature: <a href="https://www.nature.com/collections/afbgiddede" rel="nofollow">https://www.nature.com/collections/afbgiddede</a>. They're also hiring an SRE:<p><a href="https://broadinstitute.wd1.myworkdayjobs.com/en-US/broad_institute/job/Cambridge-MA/Site-Reliability-Engineer_2343" rel="nofollow">https://broadinstitute.wd1.myworkdayjobs.com/en-US/broad_ins...</a><p>Lots of other jobs at various levels throughout the institute. Biology knowledge generally note required (I had none), although it helps (but be prepared to learn).
> I wanted to find not-so-popular companies working on hard tech, long term problems<p>You won't find many. By definition what you're describing is incredibly expensive and without an immediate return. So the only groups that can afford work on these kinds of problems are academics, big companies with large R&D budgets or organizations like NASA or CERN. Any small company that attempts this will just go broke very quickly.
"Hard tech long term problems" is the domain of university research groups typically and small research groups inside big corp quite often, especially if the solution of these problems is expected to require years and to be not profitable at all until then