TE
TechEcho
Home24h TopNewestBestAskShowJobs
GitHubTwitter
Home

TechEcho

A tech news platform built with Next.js, providing global tech news and discussions.

GitHubTwitter

Home

HomeNewestBestAskShowJobs

Resources

HackerNews APIOriginal HackerNewsNext.js

© 2025 TechEcho. All rights reserved.

What the Heck Happened to John Ioannidis?

17 pointsby amirmasoudabdolabout 4 years ago

4 comments

jfengelabout 4 years ago
I&#x27;m surprised people are surprised. He&#x27;s mainly known for a paper called &quot;Why Most Published Research Findings Are False&quot;, a deliberately misleading title that sparked a ton of pseudoscience. It didn&#x27;t tell scientists anything they didn&#x27;t already know, and it misinformed anybody who wasn&#x27;t a scientist.<p>So we have a person who likes to be contrary, and gets famous doing it. It comes as no surprise that he would put contrariness over research, and do shoddy work in the process. Then he can claim that he&#x27;s &quot;outside the orthodoxy&quot;, a favorite tactic of cranks and quacks, and appealing to everybody who doesn&#x27;t know science and enjoys imagining that the scientists are bad at their jobs.
评论 #26662074 未加载
alan-croweabout 4 years ago
When it comes to momentous public policy decisions, such as closing down much of the economy, or shutting schools, it is important to use the right metric. Counting deaths often works. If deaths are evenly spread across age and health, so that some young children as losing parents, while others are losing grand-parents, a plain count of deaths tells most of the dreadful story.<p>But with COVID deaths are concentrated among the frail elderly. Young children are losing grand-parents, but not the ones that take them to the swing park. It is the frail old ones, or even the great-grandparents. Rather than using a plain count of deaths, we should be looking at Quality Adjusted Life Years lost.<p>There is perhaps a factor of ten at issue here, between a pandemic like the flu that followed the Great War and which killed healthy young people, and our own pandemic. When a healthy young person dies from a cytokine storm perhaps 50 QALYs are lost. When a frail old person dies at 80 instead of 85, perhaps 5 QALYs are lost, or fewer.<p>The article goes with a plain count of deaths. But the article is accusing John Ioannidis of &quot;minimize the dangers of the coronavirus&quot;. If the article were accusing Ioannidis of exaggerating the dangers of the corona virus it would hardly matter that the authors own crude approximation over-stated the danger. We would reason transitively. The author over-states the danger, the author says that Ioannidis puts the danger higher than the author does; as readers, we are persuaded that Ioannidis puts the danger higher than he should.<p>But the logic here is the wrong way round. The author is taking a crude, approximate approach, that over-states the danger of the coronavirus by perhaps a factor of ten. Of course he will accuse others of minimizing the dangers. And as readers, we are disappointed that sciencebasedmedicine.org is so careless with the quantitative aspects of mortality.
mdpopescuabout 4 years ago
He went against the consensus. You cannot go against the consensus.
评论 #26664319 未加载
rurbanabout 4 years ago
He published the correct IFR of 0.20 - 0.30%, which was known to every scientist since April 2020, but nobody dared to speak against politics and its agents who published numbers 10x as high. Everyone talked about a CFR of 3-5% and aburdly wrong models and predictions. The measurable good (baysian) models were ignored. Scientists who spoke out were censored, ridiculed or even fired from their jobs.<p>So of course he is evil for daring to counter the liers.<p>Now everyone should know that they lied, and Ioannidis was right. But politics are afraid of a right wing takeover. Rightly so, they should. We are at an IFR of 0.17% currently. We have an absurdly high percentage of asymptotic cases, and we don&#x27;t know the rate of false-positives of PCR tests. The EMA lies, AZ lies, who knows who else. You can only read scientific papers or medical journals, the press and politics are far off. With 3 mill dead over 2 seasons it&#x27;s still in the range of a normal strong flu season. A strong flu season has 0.650 - 2 mill deaths (per year, we have 2 seasons now, a 3rd expected), a normal season has 290.000 - 650.000.
评论 #26663995 未加载
评论 #26664244 未加载