Combining a few recent HN topics. I bet you could reverse engineer a prion to develop the mRNA to create it. Pack that gene into something like SARS-CoV-2 that's highly transmissible but maybe not quite as loud in the body. Let it burp prions into your system while it's humming away then in a year or two a couple billion people die of spongebrain.
A Flu Virus Risk Worth Taking (2011)<p>-By Anthony S. Fauci,
Gary J. Nabel and
Francis S. Collins<p><a href="https://www.washingtonpost.com/opinions/a-flu-virus-risk-worth-taking/2011/12/30/gIQAM9sNRP_story.html" rel="nofollow">https://www.washingtonpost.com/opinions/a-flu-virus-risk-wor...</a>
Related:<p>Inside the Chinese lab poised to study world's most dangerous pathogens (2017) Nature<p><a href="https://www.nature.com/news/inside-the-chinese-lab-poised-to-study-world-s-most-dangerous-pathogens-1.21487" rel="nofollow">https://www.nature.com/news/inside-the-chinese-lab-poised-to...</a>