The tone of this article strongly implies the technique will only work for foundational facts, unless you gamify it into the goal of the exercise in the first place: The investment of time to learn a random 52 card deck order only pays back if you can monetize the order of that specific deck.<p>Learning complex chromatic chord sequences, plays back literally as you make music. Memorising the score, or the script of a play, pays back in the (repeated) performance.<p>I think memory palaces are wonderful, but if you want to hold onto some ephemeral knowledge in a corner of your discipline and only refer to it twice in 20 years, the cost:benefit might not pay out.
I have never tried memory palaces, but I have always wondered if the application of automated memory palaces in VR would work and make the process more efficient.