Perhaps some good news from a paper out of Japan: <a href="https://twitter.com/SystemsVirology/status/1474759694971727872?s=20" rel="nofollow">https://twitter.com/SystemsVirology/status/14747596949717278...</a>
"The 6th preprint from G2P-Japan - #Omicron is less infectious and pathogenic than #Delta and even an early pandemic SARS-CoV-2 in infected hamster model."<p>Note: less infectious here means intra-cell, it's still more transmissible than Delta.<p>Another thread summarizing what this means: <a href="https://twitter.com/sailorrooscout/status/1475097966939721729" rel="nofollow">https://twitter.com/sailorrooscout/status/147509796693972172...</a>
Is there any evidence that shows that omicron is even particularly dangerous?<p>There has a been a “savior” strain that a lot of us have been hoping for which is: extremely transmissible, and relatively benign. So far it seems like omicron could be that, but I haven’t actually seen good data on mortality yet.<p>If anybody has good mortality data I would love to see it.
This is completely untested but i would assume that the more times you get infected or vaccinated, the more resistance you get to subsequent infections. The alternative is that covid variants keep reinfecting people over and over and people who just barely make it out of the hospital come back, which is <i>really</i> bleak.<p>So Omicron is reinfecting people but it’s not as severe, not only because of specific mutations, but because most people have already been infected / vaccinated multiple times.<p>This would also apply to other diseases. So if someone has been infected with e.g. the flu 5 times, it debunks this theory. IIRC there are multiple common colds which would explain why some people get sick with cold almost every year (and even then infections tend to be spread out). Anecdotally there was one time i was infected with some sort of stomach bug 4 times in a short span, but i’ve never had a stomach bug since then.
Not just pfizer, everything, MABS and including previous infection too<p><a href="https://www.nature.com/articles/d41586-021-03796-6" rel="nofollow">https://www.nature.com/articles/d41586-021-03796-6</a><p><a href="https://www.nature.com/articles/d41586-021-03826-3" rel="nofollow">https://www.nature.com/articles/d41586-021-03826-3</a><p><a href="https://www.medrxiv.org/content/10.1101/2021.12.22.21268021" rel="nofollow">https://www.medrxiv.org/content/10.1101/2021.12.22.21268021</a><p>The question is if you get omicron can you then turn around and get delta which is still out there, just being out-competed at the moment.
Recommendation of boosters is short-sighted and is only valid while this variant is active. Give vaccines to Africa instead so there will be no new variants. A first dose is much more valuable than a third
<a href="https://ourworldindata.org/mortality-risk-covid" rel="nofollow">https://ourworldindata.org/mortality-risk-covid</a><p>It would appear that mass vaccination had a minimal effect on the already low case fatality rate. I think it’s getting harder and harder to justify lockdowns and forced masking.