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Covid spike protein induces cognitive deficit and anxiety-like behavior in mice

59 pointsby IdEntitiesabout 3 years ago

11 comments

Gatskyabout 3 years ago
&gt; Eight-week-old mice were used for the spike protein injections. S1 protein was purchased from Acrobiosystems (Cat #S1N-C52H4, Newark, DE, USA), and used after polymixin B (Cat #P1004, Sigma-Aldrich, St. Louis, MO, USA) treatment (30 µg&#x2F;ml). The animals were anesthetized with isoflurane, and the injection paths were drilled into their skulls. Then, 5 µg of S1 protein (1 µg&#x2F;µl) were bilaterally injected into each hippocampal region using a Hamilton syringe (Cat #80330, Hamilton Company, Reno, NV, USA) attached to a syringe pump (Cat #53311, Stoelting Co., Wood Dale, IL, USA) at a constant volume of 0.5 µl&#x2F;min.<p>I think we can all agree that injecting huge amounts of viral protein into your brain is not recommended.<p>This study did not include a control group which received non-spike protein viral antigens (from say influenza which is also known to cause neurocognitive problems). As such it does not prove any specific neurotoxic effect of Covid19. The mechanistic studies in the paper suggest it is non-specific inflammation which causes neuronal cell death.
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thenerdheadabout 3 years ago
It took me a little over a year to feel back to normal. That’s cognitive function and reduced anxiety. It introduced depression and anxiety to my life that I never had prior. I’ve had to learn to cope with this and sought solutions every new day. What helped me most was exercise, little to no mainstream news or social media, and getting clearer on my purpose of life. It was a very rough 14 months, but I got through it and feel back to normal.
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thanatos519about 3 years ago
Over here, too! I feel like I&#x27;ve had a lobotomy and even after the other symptoms were gone, I have been sleeping an extra 6h a day. I feel like I need a little nap and wake up 3h later.
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civilizedabout 3 years ago
Reminds me of the study that said long COVID symptoms were strongest in people who thought they had COVID but never actually got it.<p>Some areas of science experience a lot of swirl. Eggs are good for you on Tuesday and bad for you on Thursday.
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smegsicleabout 3 years ago
<a href="https:&#x2F;&#x2F;hnrankings.info&#x2F;30901029&#x2F;" rel="nofollow">https:&#x2F;&#x2F;hnrankings.info&#x2F;30901029&#x2F;</a><p>dropped from 4 to 33 between 23:00 and 23:05
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flenserboyabout 3 years ago
And that&#x27;s part of why it&#x27;s best to stay as far away from this virus and its nasty little bits as possible, no matter its method of entering the body.
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Traubenfuchsabout 3 years ago
What about the proteins the mrna and vector vaccines turn your cells into factories for, at various locations in your body, for a various amount of time?<p>Is there a difference?
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Traubenfuchsabout 3 years ago
Does the same happen to humans?<p>Does that kind of damage heal in the majority of humans?<p>How long does healing usually take?
ajmaabout 3 years ago
Good thing I&#x27;m not a mouse
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tonymetabout 3 years ago
better late than never i guess .
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emergedabout 3 years ago
Our entire family was sick and it crushed us for 2-3 weeks. This description sounds like it applies to us too. I take anxiety medicine and it’s like it completely stopped working. Yet none of us tested positive for COVID.<p>I don’t know what that means. It could mean we had COVID but the tests were wrong. It could mean we didn’t have COVID but the flu had similar impact.<p>Just have no idea what to think about anything anymore.<p>Edit: downvote away. This is my literal life as it occurred. I’m not making a political statement I have absolutely no idea what to make of it.
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