What about A, B, C, D, E, F, G, J, K, L, M, N, P, Q, R, S, T, U, V, W, Y and Z?<p>Seriously, they're all real single-letter languages (Google for "[letter] programming language" and wade through the results).<p>I knew of only about 5 of them already (B, C, D, E, K). I couldn't find real languages for H, I, O or X.