My 8th post about AlphaFold’s and its impact on R&D
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Generative AI - Short & Sweet 08
“We (humans) are very bad judges of the impossible.”
- DeepMind.
The GAI topic of the week is ..
AlphaFold by Google DeepMind (GDM). A model that accurately generates complex 3-dimensional protein structures with correct folding from a 1-dimensional string input only. The impact this model has on research & development in all kinds of areas is unparalleled.<p>For visual learners, these are AlphaFold’s results of generated proteins measured against experimental results: highly accurate.<p>Remarkable milestones
Leading to GDM’s AlphaFold and its wide success, there are a couple of milestones worth mentioning. Disclaimer: there are many more important events that happened, but I try to stick to the newsletter’s title, which I am already bad at.<p>1996 - Deep Blue by IBM literally a tower computer won against Garri Kasparov the long-time world champion in chess [1].
Number of possible moves in chess: 10^120 (a one with 120 zeros) aka the Shannon number.<p>2016 - AlphaGo by GDM won in a series of Go matches against the former world champion Lee Sedol. Go is a complex Chinese board game with a 19x19 grid [2].
Number of possible moves in Go: 10^172 and, comparatively if not heard yet, there are 10^82 atoms in the universe.<p>2019 - AlphaStar by GDM reached the grandmaster status in StarCraft II. StarCraft II is one of the most challenging real-time strategy games. It has an unlimited number of moves [3].<p>2020 - AlphaFold 2 by GDM scored above 90 for proteins in CASP's global distance test, the Olympics of protein folding. This is a test that measures the degree to which a predicted structure is similar to the determined structure in lab experiments, with 100 being a complete match. With a score of 90, this problem is considered solved [4]. With this result, AlphaFold is around 3 times better than previous solutions.<p>The last one is especially interesting because everything in a prediction of protein folding has to be exactly right. Nature is much less forgiving than a game where perhaps not every move has to be executed perfectly.<p>AlphaFold’s gift to humanity
Usually, it goes like this: a company solves a problem and - rightfully so - monetizes it. The harder the problem solved, the higher the price. Especially, when there is demand. .... Continue on newsletter page.