I don’t drink anymore, but as I got older the hangovers got worse. I looked for different alcohols (low sugar wine) which improved things but every single digit “n” times I drank I’d have a terrible hangover. I figured there’s was an emotional vulnerability component involved.<p>When pot was legalized I went through all the pot options, but even one drag on a pot vape would leave me with an altered hangover physical feeling the next day.<p>I just stopped chasing an altered state, or one beyond coffee, and working out more.
About twenty-five years ago I product tested a hangover prevention pill that appears to have been little more than capsules of activated charcoal. IIRC, we were instructed to take one pill before drinking and then one after every other drink. If it wasn't the drunkest I've ever been, it was close. The next day I was low on energy but was otherwise unaffected by the previous night's drinking. As one of my fellow product testers put it "I feel unreasonably ok". I suspect that the product didn't take off because activated charcoal can interfere with absorption of things you want absorbed, like prescription drugs and also because it turned your poop absolute jet black.
> A third of a bottle of tequila is probably not what you would consider a wild night out<p>This is sad to see. You know what’s better than binging on hangover-free alcohol? Not binging in the first place.
NAC has been very helpful for me. I have no idea if it really works, but it is the best option I have found.<p>It’s really hard to evaluate the author’s experience because we don’t know “what a little tired” means or how much alcohol the bar put in his drinks. A BAC reading before bed would have made this more credible.
This is interesting - however as someone who used to enjoy mild drinking and just lost interest in booze, it's still worth stating that alcohol is definitely still bad for the body in a myriad of ways.<p>2022 was my first completely dry year - health and mental clarity has never been better even in my late 20s.
Isn’t GHB hangover free alcohol (other than the part where you can date rape people with it).<p>The real downside is that when these drugs are hangover free it’s basically like Xanax (which shares a similar chemical property to alcohol), and it’s very addictive. Alcohol is already extremely addictive
It doesn't specify the actual ingredients. The "grapes" bit makes me think perhaps resveratrol?<p>Dihydromyricetin is touted as being protective before and after drinking. It appears to have other benefits as well.<p>I've now become a big fan and follower of Andrew Huberman and a recent podcast has helped sway me to effectively give up alcohol (I was already trending in that direction): <a href="https://www.youtube.com/watch?v=DkS1pkKpILY">https://www.youtube.com/watch?v=DkS1pkKpILY</a><p>My one remaining active vice is Kratom and I'm pretty comfortable with my relationship with it, considering the value it gives in managing chronic pain. Obviously different strokes for different folks.
for someone purportedly so intent on having a scientific experiment, he didn’t seem to be bothered by the fact that these two days of drinking were in a row<p>if I drink on consecutive days the hangover will be markedly weaker on each additional day
Weird… I tried this literally last night.<p>Not his product. But drinking green tea while drinking alcohol to see if it prevents hangover via antioxidants.<p>Currently writing this from bed… I feel good. Needs more experimentation. More potent antioxidants.
I wonder how the results compare with ZBiotics. Extracting anti-oxidants from grapes seems like a more down-to-earth process than genetically engineering probiotics, but with the probiotic approach you don't need to get bartenders & liquor companies on board in order to benefit.
Supposidly the Chinese spirit Maotai is known for its lack of hangovers.<p><a href="https://en.wikipedia.org/wiki/Maotai" rel="nofollow">https://en.wikipedia.org/wiki/Maotai</a>