Access is going to be the issue here.<p>My doctor recently put me on tirzepatide. It needed a prior auth from my insurance despite me being under treatment for type 2 diabetes for the last five years. My pharmacy benefits plan requires all prescriptions be sent to a mail order pharmacy, so I asked him to send in there. The mail order pharmacy accepted the script and offered to fill it for $3,000 for a one month supply. I asked them why, and they said that prior auth was still pending. Two days later, prior auth was denied with no reason given when I called.<p>Two days after that, prior auth was approved and the mail order pharmacy now wanted to charge me $25 for a three month supply.<p>Access to this drug for most people will be a nightmare, even for those that could benefit from its on-label use for type 2 diabetes.
This looks like a wonder drug.<p>On social media there seem to be two types of deniers:<p>1. People who make stuff up about it. Even Peter Attia said in an interview recently that you lose more lean mass than fat on the drug.<p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089287/" rel="nofollow">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089287/</a> "Greater weight loss was associated with greater improvement in body composition (lean body mass:fat mass ratio)."<p>2. People who think it's an unfair shortcut to lose weight with a pill. That fatties should just have to exist until they can make the identity level genetic changes on their own to lose it.<p>Both cases are sad to see especially if you've been someone who has- or watched a loved one- struggle to lose weight their whole life.
>Tirzepatide, an Eli Lilly and Co. drug approved to treat type 2 diabetes under the brand name Mounjaro, helped people with the disease who were overweight or had obesity lose up to 16% of their body weight, or more than 34 pounds, over nearly 17 months, the company said on Thursday.<p>Is 34 pounds over 17 months really that significant? I lost that much in 6 months on a ketogenic diet, even with a lot of cheating (alcohol, fried chicken).