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Ask HN: How do signalling molecules find their targets at large/dense distances?

1 pointsby spacetimeuser5about 2 years ago
Though it is understandable that a biology question may be a bit out of range at HN, but maybe you can repurpose some of the data collection and thought algorithms for this question or have a chance to ask someone experienced in biotech etc.<p>Some time ago I asked a question at biology stackexchenge [1], and it seems it hadn&#x27;t received a comprehensive answer.<p>Additional context is that there are ~10K biochemical reactions happening in ~every cell per second and for a signalling molecule to get to its target it needs to get through a rather dense intercellular milieu.<p>[1] https:&#x2F;&#x2F;biology.stackexchange.com&#x2F;questions&#x2F;88735&#x2F;how-do-signalling-molecules-find-their-receptors-at-large-distances

1 comment

rolphabout 2 years ago
specific signaling, is transported from origin to insertion point by way of ~ persistent &quot;tracks&quot;<p>[1] below is probably most directly relevent to what your asking, but finer detail is here [2][3]<p>[1] <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Intracellular_transport" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Intracellular_transport</a><p>[2] <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Cell_signaling" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Cell_signaling</a><p>[3] <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Signal_transduction" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Signal_transduction</a>