The CNN article seems not to justify the claim of "change". The experiment appears to demonstrate that obese people's brains do <i>this</i>, while non-obese people's brains do <i>that</i>, but the inference that the obese brains started out just like non-obese brains is unsupported.
<i>Obesity may damage the brain’s ability to recognize the sensation of fullness and be satisfied after eating fats and sugars, a new study found.</i><p>I think metabolic changes and hyper-palatable foods better-explain obesity compared to faulty satiety/fullness signals. Slow metabolisms due to age or genes combined with hyper-palatable foods, such as carbs and fats combined, are a recipe for obesity.