The important lead paragraphs:<p>> Giving young children the world’s first malaria vaccine RTS,S/AS01E alongside antimalarial drugs before the rainy season has led to a significant reduction in life-threatening malaria cases and deaths for over five years, according to a landmark study.<p>> Results published in The Lancet Infectious Diseases show the vaccine-drug combination reduced clinical malaria episodes, including cases of severe malaria in children and deaths, by nearly two-thirds compared with either method given alone in settings of highly seasonal transmission.<p>> The study began in 2017 in Burkina Faso and Mali, two countries with a very high burden of malaria, and followed more than 5,000 children over a total of five years.<p>Like pretty much anything involving malaria, I'd say this is a temporary victory at best. Malaria has a long history of developing drug resistance. And vaccine resistance could well prove similar.