This is an interesting and novel paper. Speaking as a biophysicist, I see potential applications in the regenerative medicine space with cartilage and/or joint replacement. There could be also applications in the field of dermatology with aging therapies or skin grafts. More speculatively, one can imagine scientists developing superior types of joints or connective tissues than the ones evolution has landed upon.
What's the potential to weaponize such advances, say by creating novel prions and so on? I assume powers that be are already playing with the tech hidden away in their bunkers?
Maybe off topic, but what means "de novo"? (in Portuguese it means "again" but I can't make sense of this)<p>This article <a href="https://en.wikipedia.org/wiki/De_novo_protein_structure_prediction" rel="nofollow">https://en.wikipedia.org/wiki/De_novo_protein_structure_pred...</a> also doesn't mention the etymology