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Ask HN: Have you tried weight loss drugs?

15 pointsby slayerjain12 months ago
I just saw the recent South Park episode which talked about weight loss drugs but they didn’t take any clear stand on the matter. In fact I thought they were mostly positive about it.<p>Can you please your practical experiences with them?

9 comments

dyingkneepad12 months ago
To me what worked was going the slow route: do small but *permanent* adjustments to the diet in order to slowly decrease calorie consumption. This is the path that is safest against eating disorders.<p>Having soda 5x per week? Well, let&#x27;s see if I can survive a month doing it only 3x per week. Perhaps later replace it with the Zero version, or buy a smaller bottle. Once I do one step and &quot;stabilize&quot; on it, then I can further reduce consumption.<p>Pay attention to what times of the day I am eating but not that hungry. I concluded that having just 1 slice of bread at breakfast (instead of 2) didn&#x27;t make any difference at all, so I did that permanent change. It&#x27;s just 70 calories, but it&#x27;s 70 calories I was able to cut at basically no effort.<p>Recognize about how many calories each of the things you do have. Always start the optimization with the liquid calories: soda, juice, starbucks-like stuff, alcohol. Don&#x27;t go hardcore and fully get rid of anything: reduce amount, frequency, try to substitute. I still love donuts, I still eat donuts: I&#x27;ll never take this away from my menu. But I don&#x27;t eat 5 donuts in a single seating, and I don&#x27;t eat donuts every week. Chocolate was way easier to dramatically cut: I like it, but not that much. I have no idea why I ate M&amp;Ms: it&#x27;s not even that good, but it was available (as my son loves it), so I just ate it without thinking. I don&#x27;t anymore.<p>Same with exercise: I bought a stationary bike and my first goal was to do 15 minute sessions 2x per week, while watching youtube. I soon realized I could do 20 minutes every other day. Now I also do a small amount of weight lifting 1x per week after the bike. Also recognize that the goal of the exercise is *not* to burn calories, as calories burnt by exercise area way too little. By developing muscles you increase your base metabolism, and that&#x27;s the biggest help. Also you get healthier and your day gets easier.<p>One small step at a time. Permanent changes. That will get you there eventually. This is a really good path, unless your doctor is screaming at you saying you need to lose weight immediately or you&#x27;ll die. Try it.
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talkingtab12 months ago
Once when I was still smoking, I ran a 10K run and then had a cigarette. Some part of me, said &quot;how stupid is this&quot;?<p>We have a corporate food system that promotes obesity. Now other corporations want us to pay $1000&#x2F;month to &quot;cure&quot; obesity. How stupid is that?<p>Go to a grocery store, measure the frontage into three categories:<p>- directly obesity inducing (soft drinks, chips, candy, flavored, sugar drinks, etc)<p>- processed and obesity inducing. Frozen meals. Mac and cheese, anything with added fat, sugar. How much salt induces obesity? Will meat from animals that have been given growth enhancers then enhance your growth? Will meat ground with fat induce obesity?<p>- healthy. Fresh vegetables, fruit, beans etc.<p>Now here is the question for you? Which of these groups make the most profit to the supplier? And does that align with the groupings above?<p>At my grocery store that we literally have less that one side of one aisle of fresh fruit and vegetables. And even there, more and more of the space is taken by packaged veggies - chopped lettuce with included salad dressing etc.<p>Our perception of our food system is whacked out. &quot;a dominant theme has been that we have the safest food supply in the world.&quot; [<a href="https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;books&#x2F;NBK209121&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;books&#x2F;NBK209121&#x2F;</a>], and yet we have an epidemic of obesity. How safe is obesity?
instagib12 months ago
1.Ephedrine Caffeine Aspirin (old ECA stack)<p>2.MuscleTech Vapor X5<p>3.“Truck stop speed”<p>Just my experiences, not recommendations or advice, do your own homework.<p><a href="https:&#x2F;&#x2F;youtu.be&#x2F;_3-Vlql2ivM" rel="nofollow">https:&#x2F;&#x2F;youtu.be&#x2F;_3-Vlql2ivM</a> James Smith - burning 5000 calories then eating 5000 calories. He also has a video on clenbuterol “fitness industry secret weapon”. Generally helpful exercise&#x2F;weight loss advice videos.<p>1: used for boosting exercise and losing weight. Good for boosting energy and the combo reduces caffeine crash. A few sports players have died from using it + bad hearts. It’s still accessible. Seemed like I could eat a massive amount of clean food with a good ratio of protein&#x2F;fat&#x2F;carbs, gain strength, and the weight gains were clean while losing waist inches. Tracking body measurements were necessary.<p>2: exercise and losing weight. Very good stimulant effect and to hit new personal records. Can give headaches so I cut the dose to 1&#x2F;4 or 1&#x2F;2. Great for overcoming the not wanting to work out days which leads to more exercise days per week and a more healthy lifestyle.<p>3: hard to tell what is really in it. Possibly something illegal but if you work 12 hours and need to then drive 12 hours to get home without falling asleep, this was what I would reach for. Found at the checkout counter at popular truck stops.
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daly12 months ago
My kids call it my &quot;Dad-kins&quot; (a pun on Atkins) diet.<p>Buy a scale. Record your weight. (e.g. 200.0lbs)<p>Week 1: you can eat anything you want in one sitting if the scale shows less than 200.0lbs<p>Week 2: you can eat anything you want in one sitting if the scale shows less than 199.9lbs (200.0-0.1)<p>Week 3: you can eat anything you want in one sitting if the scale shows less than 199.8lbs (199.9-0.1)<p>...<p>Week X: you can eat anything you want in one sitting if the scale shows less than (last week&#x27;s goal - 0.1)<p>So losing a pound takes 10 weeks. Losing 10 pounds takes 100 weeks, etc.<p>The subtle part is that<p>(a) you can only eat when the scale says so which means that grabbing junk food gets ruled out unless the scale agrees.<p>(b) you don&#x27;t feel &quot;deprived&quot; because you can anything you want in one sitting.<p>(c) you discover that eating junk food at your &quot;one sitting&quot; just means it will take longer before you can eat again.<p>(d) because you&#x27;re SLOWLY changing your eating habits using external measurable control your body will lose weight and keep it off, gradually starving those fat cells.<p>(e) this is a &quot;diet&quot; in the sense of changing your eating habits, not in the current perverted meaning of trying to &quot;diet&quot; by &quot;crashing&quot; your weight loss.<p>Eventually you&#x27;ll discover that if you skip anything containing high fructose corn syrup you tend to get to eat more frequently. That HFCS really hurts.
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dc_ist12 months ago
If you can withstand the first few days, a lo carb &#x2F; zero carb diet will do wonders for your appetite. I don’t know what the long term impacts are of such a diet but I do know from personal experience that it’s drastically improved my ability to withstand cravings.
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muzani12 months ago
Anecdotally,<p>Garcinia seems to be the most useful so far, mostly by lowering appetite.<p>Fat burners mostly rely on 1) increasing metabolism via caffeine 2) making that effect last longer. It seems to make things worse for me by increasing hunger, and sometimes makes me feel tired like when I have a fever and I end up lying around all day. Fevers burn lots of calories too, so I suspect it&#x27;s artificially creating the same effect. It&#x27;s probably most useful when combined with workouts. Also I think a lot of programmers have higher caffeine tolerance.<p>Things that keep blood sugar low are very effective in reducing weight but part of it is done by reducing water. Side effect is your brain needs plenty of sugar for processing, so it was not suited to programming work.
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dotcoma12 months ago
&gt; but they didn’t take any clear stand on the matter.<p>So, you refer to South Park for medical advice ?
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palata12 months ago
Whenever I have a discussion about weight loss, I like to share this TEDx video: <a href="https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=vuIlsN32WaE" rel="nofollow">https:&#x2F;&#x2F;www.youtube.com&#x2F;watch?v=vuIlsN32WaE</a><p>Just because I think it is quite interesting, not trying to make a point or anything :-).
palata12 months ago
What about eating healthier and doing more sport? I heard it works pretty well.
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