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Large language models identify causal genes in complex trait GWAS

2 pointsby auton112 months ago

1 comment

auton112 months ago
"Here, we demonstrate that large language models (LLMs) can accurately identify genes likely to be causal at loci from GWAS. By evaluating the performance of GPT-3.5 and GPT-4 on datasets of GWAS loci with high-confidence causal gene annotations, we show that these models outperform state-of-the-art methods in identifying putative causal genes."