There's no reason for this to be a NYT link.<p><a href="https://www.fda.gov/news-events/press-announcements/fda-approves-novel-non-opioid-treatment-moderate-severe-acute-pain" rel="nofollow">https://www.fda.gov/news-events/press-announcements/fda-appr...</a>
>>suzetrigine helped those with diabetic neuropathy, but was no better than placebo in those with pinched spinal nerves.
(…) While analysts and researchers deemed the results disappointing in patients with pinched nerves in their spines, the company decided to proceed because there are no approved drugs for the painful condition, and because the drug is safe and “the mechanism of action is so clearly validated.”<p>“No one has ever helped these four million people,” he said. <<<p>Aside from routinely burning the nerves, routine epidural injections, narcotics, or alcohol.<p>Extremely limited relief from expensive acupuncture, massage, TENS, stretching, etc.
How does one give someone a placebo after surgery for clinical trials ? Wouldn’t that cause a lot of pain ? I know science and research and trials and all etc etc, but pain post surgery is quite a lot that placebo alone would be really bad for the patient.
Note that there is a fairly long list of CYP3A4 inhibitors that this is contraindicated against. I know nothing is, but this won't be for everyone.
Super exciting development in the world of medicine, but the price tag is really steep. Starting at US$15.50 per pill, and you're supposed to take two pills at a time. Many will opt for cheaper options.<p>Disclaimer: I'm Canadian with extended insurance, so I have little perspective on drug prices.