Sadly that reminds me how positive covid antibody test results haven't been a valid immunization attestation.<p>Maybe this type of bispecific antibodies could be used to neutralize the spike protein which the body produces through the vaccine. As far as I understand the targeted deltoid muscle is a cell with a long life therefore procuding and releasing spikes for a yet unkown timeframe. Given the various specific boosters I can imagine one taking neutralizing antibodies to avoid a constant immune system stimulation.
The title is "Bispecific antibodies targeting the N-terminal and receptor binding domains potently neutralize SARS-CoV-2 variants of concern". Note that although the antibodies were only helpful before infection, "its therapeutic efficacy after infection was limited." Thus, it isn't a treatment. Also, this study was in mice, not humans, so this is something potentially for the future, not something you can use now.
All variants? but N-Terminal is not immune to mutations and the specific antibody will drive evolutionary selection for those mutations - and rapid development of new variants<p><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC8647783/" rel="nofollow">https://pmc.ncbi.nlm.nih.gov/articles/PMC8647783/</a> search "N-Terminal"
I'm amazed by how virtually every single biology paper in a great-to-elite journal has stunning figures (even setting aside the protein diagrams). This makes me wonder how much of advisors' efforts go toward teaching their students graphic design
Also of note because of recent political choices, these are humanized mice, meaning they're transgenic. They have a human ACE2 gene instead of the mouse ACE2 gene, which makes the human version of the enzyme that the COVID virus uses to enter cells. This isn't my exact field, so I'm not positive, but I remember hearing that all of the COVID mouse models require transgenic mice.