I am excited to finally after some near 30 years that research is taking a serious look into the role creatine could play for better mindset. I have myself urged people I know that could be depressed to try small doses but ask their doctor first. Sadly none have ever told me it made a difference for them.<p>My experiment with taking it was very clear - long story short, after reading an article in <i>New Scientist</i> mid 90s, took small doses in the hope it'd help repair some weakened muscle due to injury. After some time, (don't recall) I noted a few improvement in other things, immune system but in particular an improvement in my mind set/ outlook - finding nearlly all my days my mood was very mellow and not wasting so much time chewing on BS catty remarks and other stuff. I wouldn't say I had been depressed per se but had been in a very dark place - my GP at the time barely raised an eyebrow when I informed them of the remarkable difference in my mindset. I thought it was fairly stark difference though dealing with when the day went snafu fubab, mellow is quite apart from being POed - for those of you who remember <i>Daria</i> - think a younger version of Anthony DeMartino - blood shot eye even as I ranted when some idiot or something else had really poked the day.