IMO, the really interesting bit is this:<p>> The authors of the new study suggest that Rev-erbα affects muscle cells by promoting both the creation of new mitochondria (often referred to as the “power plants” of the cell) and the clearance of those mitochondria that are defective.<p>There's a research trend focusing on muscular strength and mass decline in aging, tied to reduced mitochondrial activity[1]. I'm hopeful that treatments along the lines of those described will produce improved physical and cognitive quality of life for an aging population.<p>[1] E.g. search for journal article hits on "muscular strength mitochondria aging" and similar.