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Microbe computers

45 pointsby aethertapover 11 years ago

4 comments

lognover 11 years ago
If we want bio computing to take off, somehow we need an IDE for this stuff. I thought following install instructions for typical software was hard, check this out:<p><a href="http://openwetware.org/wiki/ChIP-Chip_E._coli" rel="nofollow">http:&#x2F;&#x2F;openwetware.org&#x2F;wiki&#x2F;ChIP-Chip_E._coli</a><p>edit:<p>found this: <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989930/" rel="nofollow">https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC2989930&#x2F;</a><p><i>BioCoder, a C++ library that enables biologists to express the exact steps needed to execute a protocol. In addition to being suitable for automation, BioCoder converts the code into a readable, English-language description for use by biologists</i>
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lifeisstillgoodover 11 years ago
This feeds into one of my pet questions : will Moore&#x27;s Law really die?<p>Doubling transistor density on silicon will end about 2020&#x2F;22, when 7 or 5nm etching occurs - beyond that and chip designers are past the wavelength of red (?) light and into quantum tunnelling effects<p>But ...<p><i>maybe</i> the amount of CPU cycles available to use for a given bi-annual price will keep doubling. More efficient systems on a chip, cooling in huge data centers means Siri can keep doubling its ability to run voice analysis on my behalf?<p>is that true?<p>3. is there genuinely any chance things like bio-computing?
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jonmrodriguezover 11 years ago
Hurray, Dr. Endy, Monica, Jerome, and Pakpoom! :) I interned in this lab and it&#x27;s really cool seeing their amazing work (especially using M13 for high-bandwidth communication) get the press it deserves<p>Let&#x27;s also not forget Paul Jaschke! <a href="http://www.researchgate.net/profile/Paul_Jaschke/" rel="nofollow">http:&#x2F;&#x2F;www.researchgate.net&#x2F;profile&#x2F;Paul_Jaschke&#x2F;</a> He was able to design and produce a working refactored version of the PhiX174 bacteriophage.<p>Refactoring in bio has the typical CS connotation of cleaning up messy code -- The natural PhiX174 has some overlapping genes that cannot be edited in isolation -- The refactored version has no gene overlaps, so the genes can be editted individually in a more rational manner.
mrcactu5over 11 years ago
if the article is too difficult to follow, there is always<p><pre><code> Adventures in Synthetic Biology </code></pre> <a href="http://www.nature.com/nature/comics/syntheticbiologycomic/" rel="nofollow">http:&#x2F;&#x2F;www.nature.com&#x2F;nature&#x2F;comics&#x2F;syntheticbiologycomic&#x2F;</a><p>That is the comic I read a Synthetic Biology REU at Princeton. At that point, Drew Endy was at MIT and our leader Ron Weiss was at Princeton.<p>People have shuffled around a bit in 7 years <a href="http://openwetware.org/wiki/Endy:Lab" rel="nofollow">http:&#x2F;&#x2F;openwetware.org&#x2F;wiki&#x2F;Endy:Lab</a> <a href="http://groups.csail.mit.edu/synbio/" rel="nofollow">http:&#x2F;&#x2F;groups.csail.mit.edu&#x2F;synbio&#x2F;</a>