I worked in small startups for many years, and then later I worked in big companies for a few years. From my own experience, I would say sleep deprivation has no point in a big company. It only makes sense in a small startup when you are trying to hit some very specific and life-altering deadline, such as a meeting with a potential investor, whose money might determine the fate of the company.<p>I recall a long stretch from 2003 to 2006 (myself and my friends were doing our own startup) where we were often working crazy hours to meet deadlines. I recall at one point a guy was going to come in and possibly invest half a million dollars -- that would have changed everything for us. I recall I worked for 20 hours, then I slept for 2 hours, and then I worked for another 20 hours, just so we could have a bug-free demo when the guy showed up. I recall another time when we had to meet with a potential investor at 12 PM on Thursday, and I started work at 11 AM on Wednesday, and I kept working, and I kept finding bugs, and I worked through the night fixing everything, and I worked right up until the meeting. Then the meeting ended at 1 PM -- I had worked 26 straight hours.<p>Sleep deprivation only makes sense in the life of the startup because that part of your life that you spend in a startup is suppose to be finite. Paul Graham covers this in his essay "How to make wealth":<p>"Economically, you can think of a startup as a way to compress your whole working life into a few years. Instead of working at a low intensity for forty years, you work as hard as you possibly can for four. This pays especially well in technology, where you earn a premium for working fast."<p><a href="http://paulgraham.com/wealth.html" rel="nofollow">http://paulgraham.com/wealth.html</a><p>Sleep deprivation will always be a part of startup life -- that is natural. You face deadlines that determine whether the company will continue to exist.<p>In a big company, sleep deprivation doesn't make sense. I made this mistake when I first moved to big companies, and it took me awhile to unlearn the habits that I had acquired at startups. In a big company, your individual contribution is no longer a large part of of what makes the company go (you can shape the destiny of a company with 4 people, but not one that has 400 people). And in a big company, there are no particular deadlines that truly determine the fate of the company -- nothing that has the same urgency as "We are running out of money so we need tomorrow's potential investor to invest".<p>In a big company, in the future, I will be cautious about working an 80 week. But if I do a startup again, I know what I am signing up for.