It really depends on what kind of business you want to build, and in what kind of market. You shouldn't even want to be a software entrepreneur, you should want to solve a problem / improve things. Some problems can benefit more from mobile than others. For example, PCs are great for high I/O tasks like authoring and formal communication, while smartphones are great for low I/O tasks such as consuming infotainment and informal communication. Most areas involve a mixture of those, and which should be your first priority depends on your area.<p>For example, meetup.com is quite PC-oriented, which almost seems odd for a new social networking platform, but being able to easily publish and read detailed meetup descriptions is critical to its success. That doesn't mean meetup.com cannot benefit a lot from mobile (I wish it did), but it shouldn't be its first priority.
It really depends on what kind of software you're doing. Games, yeah. Social networks, yeah. But mobile devices suck for any kind of document creation, and will continue to do so for the foreseeable future. The iPad is okay if you have a Bluetooth keyboard, but if you're going to lug that around you might just as well have a Macbook Air.
Am I the only one to find most mobile websites worthless? They try to be too clever and hide too much stuff. Or worse they only expose a small piece of functionality. I rented a car once and needed to look my reservation up on my phone at the counter. The mobile website would only let me book a new reservation and had no link to the desktop version. Yeah the article recommends apps over the websites. But now I have to spend time downloading something that also may have worse functionality.
Purely in terms of revenue stream, I wonder if Mobile Advert has caught on to Desktop. If you rely on advert may be Desktop is still a good place to start first?