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Research into psychedelics, shut down for decades, is yielding results

347 pointsby juanplusjuanover 10 years ago

16 comments

cubanoover 10 years ago
I took a ton of acid (blotter) in the late 70&#x27;s and early 80&#x27;s as a teen, and then again in the late 90&#x27;s (window pane and liquid eyedrops), and I just have to say, I, personally, have mixed feelings about this sort of thing being heralded as some sort of metaphysical panacea.<p>As I mentioned in a previous post, I became addicted to opiates in the mid 2000&#x27;s and lived as a zombified-but-somehow-functional heroin addict for about 4 years.<p>There is no doubt, in my personal case, that acid and mushrooms (that I often hand-picked in cow pastures after rainstorms here in central Florida) gateway-ed me into harder, destructive &quot;escapes&quot;, and for that reason, I cannot fully endorse this sort of thing.<p>I&#x27;ve had amazing trips where I literally felt as one with the group of friends I was chilling with and created deep, transcendent bonds, and I&#x27;ve had a select few shit ones where I felt totally alienated from every living soul (but not nature, interestingly) on earth.<p>They did expand my consciousness, but looking back, I see now that it introduced into my psyche a fairly deep distrust of authority and convention which, under sober scrutiny, perhaps did little to help me always successfully nagivate my life.<p>Treating the very sick and&#x2F;or terminally ill with psychedelics makes great sense to me; anything to ease those pains, but my own experience makes me want to throw at least a dart of caution into the mix when it comes to making a blanket statement about the benefits of LSD and such.
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snikerisover 10 years ago
Includes an interesting account of Robert Jesse&#x27;s (former Oracle VP, software engineer) efforts to resurrect this research:<p>When the history of second-wave psychedelic research is written, Bob Jesse will be remembered as one of two scientific outsiders who worked for years, mostly behind the scenes, to get it off the ground.
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Pyretover 10 years ago
<i>“I didn’t want there to be an easy way out,” she recently told me. “I wanted him to fight.”</i><p>Attitude that keeps everything stagnant and backwards.
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stateover 10 years ago
&quot;During each session, which would last the better part of a day, Mettes would lie on the couch wearing an eye mask and listening through headphones to a carefully curated playlist—Brian Eno, Philip Glass, Pat Metheny, Ravi Shankar.&quot;<p>This strikes me as sort of funny. For someone completely unfamiliar with this stuff I would imagine encountering it to be pretty trippy on its own.
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joncooperover 10 years ago
If you&#x27;re interested in this, check out MAPS: <a href="http://www.maps.org/" rel="nofollow">http:&#x2F;&#x2F;www.maps.org&#x2F;</a><p>They are doing a great deal to push this research forward and have been for decades.
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benten10over 10 years ago
While this is undoubtedly exciting, lets not forget what should be for us (specially people in the technology who have seen waves of the same &#x27;fad&#x27; come over and go) this paragraph from the article:<p>&gt;The first wave of research into psychedelics was doomed by an excessive exuberance about their potential. For people working with these remarkable molecules, it was difficult not to conclude that they were suddenly in possession of news with the power to change the world—a psychedelic gospel[...]It didn’t take long for once respectable scientists such as Leary to grow impatient with the rigmarole of objective science. He came to see science as just another societal “game,” a conventional box it was time to blow up—along with all the others.<p>Special emphasis on the last sentence.
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shanra88over 10 years ago
Mention of &quot;ego-less&quot; state etc sound just like the teachings of hindu masters like Ramana Maharishi, Nisargadatta Maharaj...
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superobserverover 10 years ago
Fascinating research. I just hope the same mistakes aren&#x27;t repeated and a really rigorous and robust effort is made to find what sorts of applications these substances can be used for. I&#x27;m reminded of LSD microdosing by scientists to improve innovation that had been done before, but I am unaware of to what degree it really bore any viable fruit.
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eli_gottliebover 10 years ago
I&#x27;m sure the drugs can have therapeutic uses. I&#x27;m also just as sure that they don&#x27;t reveal any kind of metaphysical Higher Reality, and we should stop addressing them as if they did. They <i>merely</i> alter your brain functioning in certain ways.
FranOntanayaover 10 years ago
&quot;The data are still being analyzed and have not yet been submitted to a journal for peer review&quot;<p>Maybe the NewYorker could have waited for that to happen.
dwaltripover 10 years ago
With the proper approach and care, these substances can be incredibly powerful and beneficial. I can&#x27;t wait until the research eventually forces the hand of those who mistakenly believe otherwise. Psylocybin and perhaps LSD should be legal on some level in our lifetime hopefully.
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lorddoigover 10 years ago
With other recent news in mind, I wonder what effect compounds like these might have on religious extremists. I wonder whether - assuming some kind of method of administration is figured out (a love bomb?) - they might stop burning people alive in cages after a decent trip.
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bunkydooover 10 years ago
As someone who has done their fair share of psychedelics - I would feel like a coward consuming these substances if I had a terminal illness. If I knew damn straight that I was gonna die, I wouldn&#x27;t want to numb it up with a substance. I&#x27;d want every minute of pain, suffering, and emotional baggage to be taken on with a sober mind.<p>But that is my personal choice. I would say it&#x27;s probably a very positive thing on the other hand for people like Patrick who never consumed these substances. DMT might be the best one for someone who is dying, as it is hypothesized that pineal gland floods an endogenous version of this chemical into your bloodstream upon death. Consuming it prior to death could potentially work as a &quot;practice run&quot; to help cope with the real thing as sad as it sounds.
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skidooover 10 years ago
I learned more about the world from DMT than in all my years of school.
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clapasover 10 years ago
TL;DR I grow magic mushrooms myself and can asure there is a mystic experience on eating them. I do not eat them often, but it helps me everytime with a new perspective.
lsdaccounthnover 10 years ago
Using a throwaway as while I&#x27;ll talk openly to some friends&#x2F;family, I don&#x27;t want my handle and lsd to show up together on Google.<p>This is a story, an anecdote, and while my view on LSD is positive as a result, definitely shouldn&#x27;t be read as an endorsement of my actions.<p>I&#x27;m the perfect example of somebody who shouldn&#x27;t go near psychedelics. I&#x27;ve suffered depression most of my life, and was recently diagnosed as bipolar, though I&#x27;ve only had two <i>real</i> manic episodes. But.. I&#x27;m also someone who does stupid things, possibly because of not just despite those things. I&#x27;ve abused coke, benzodiazepines, mdma, alcohol and weed. But never to an extent people around me might notice a problem.<p>A little while ago, I fell in love with my best friend. It was really fucking hard to deal with (after a few months of hoping it would go away I told her, talked it through and we set about trying to get rid of the awkwardness of staying friends), harder than any other life&#x2F;love problems I&#x27;ve had. For 6 months I was depressed, had no appetite.. I was forcing myself to eat one meal a day because despite never getting hungry I knew I needed to. Friends told me the appetite was related to my feelings, but I stubbornly dismissed that as pop science - meanwhile I was kind of happy about the appetite, as I was losing inches from my waist.<p>Then I took LSD for the first time. It was nothing like I&#x27;d expected it to be (in my imagination it would be like entering a new world, not just altering the way your mind works in the current world), but it was lovely. A few hours into that trip, I started thinking about my friend. I realised that while I still felt the same way about her.. it didn&#x27;t hurt any more. It was like this clarity just appeared over the situation that there&#x27;s nothing I can do about it, so I shouldn&#x27;t let it hurt me. While under the influence I realised it would probably be back to normal when I woke up the next day, but then it wasn&#x27;t. I woke up feeling the same way I had while tripping, went into the office, and by lunchtime I was feeling hungry for literally the first time in half a year.<p>Now I&#x27;m in a slightly different place. I&#x27;m no longer abusing &lt;something&gt; on a daily basis (the last thing to go was daily weed smoking). I&#x27;ve no interest in benzos or MDMA. I still love coke, but hardly ever do it (twice in the last 18 months, both times someone else&#x27;s suggestion, both times I didn&#x27;t want more the next day). And psychedelics... I haven&#x27;t done them much lately, but have an order on-route from dark net markets of LSD and DMT, largely motivated by wanting some more internal soul searching.<p>I was hugely grateful to the LSD for that effect it had on me. I&#x27;ve used it quite a few times since then, though it&#x27;s never made such an impact since. But lately I&#x27;ve been starting to feel down about her again. I don&#x27;t know if it can help me again.<p>Long story short... I&#x27;m not saying any of my actions were&#x2F;are sensible or the results deserved. Nor that LSD would help everyone who was in my situation. But as a single anecdote (and hopefully interesting story), it opened my eyes to believing in the sort of trials being described by this article. My pre-existing mental conditions mean I&#x27;m probably unlikely to get approved for anything like this, even when it reaches wider access, but if I could, I&#x27;d jump at the chance to go through psychedelic therapy with expert scientists guiding me rather than doing it on my own.<p>(Incidentally: who knows, maybe my next tab will turn me into a schizophrenic: but in the ~15 trips I&#x27;ve had on acid, I&#x27;m yet to have a single &quot;bad trip&quot;. Same goes for the few times I&#x27;ve tried DMT.)