You are scratching simultaneously on the doors of a huge semi-religious war (oops, block that metaphor!) and a seriously open set of questions.<p>(I think this has been asked zillions of times. I don't know why I feel compelled to throw in my 2 pence...)<p>It's hard to say "better" in a multi-dimensional question like this.<p>The things that seem clear are:<p>* Without the absolute simplicity of the prefix-style paren-delimited Lisp syntax, true macro power is almost impossibly hard/complex/messy.<p>* For some reason, most people find the Lisp syntax hard to internalize. (Likely due to its prefix nature.)<p>* Progress generally happens by evolution, not revolution. (Revolutions take about 20-30 years from idea to success in the market, if the latter ever happens.) C is the granddaddy of the "worse is better" philosophy that swept the computing world about 30 years ago, and, so C-style brackets are part of the "comfort zone" that most programmers inhabit. (C++, Java, Go, etc., all stay within that zone.)<p>I'm not sure you can say anything more before the discussion breaks down into endless rounds of fruitless bickering...
For many people reading and/or writing C-style is easier than s-expr (Lisp). On the other-hand it is far easier to parse Lisp than C-syntax. So really depends which perspective you are considering.<p>As a programmer you delegate the heavy lifting to the compiler and choose the language (& framework) based upon what you wish to accomplish.<p>Perhaps you could explain your motivation for asking the question. E.g. thinking about designing yet-another-new-language?