I think the narrative in the article may be a bit of a stretch (Thiel is not against creating restaurants because he thinks they are worthless, he just says they aren't profitable), but I think the conclusion is pretty much correct: the question that Thiel's arguments raise revolve around the question of "What Matters?"<p>Personally when I listen to talks by Thiel or Musk I almost wonder, do I really need to drop everything and go build rockets? But to be honest, I find working on digital products pretty fulfilling. I think it's a real craft. The deeper question of fulfilment then goes to what you're building with that craft (I've found marketing campaigns are less fulfilling than user-facing products, for example), and then the even-deeper question goes to what you want to do with your life, and then there's the yet-deeper question of how you want to interact with, and have your life experienced by, other people. At that point the question of whether you're going from Zero-to-One (what Thiel calls technology) or One-to-Many (what he calls globalization) starts to recede in importance when making personal choices.