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Nanorobots That Can Travel Down the Bloodstream and Precisely Target Tumors

204 点作者 azazqadir将近 9 年前

13 条评论

cm3将近 9 年前
Anytime we get practical implementations of ideas of the past by scientists and engineers working on it despite cutbacks in funding, I wonder where humanity would be if we at least halved the money spent on state-funded violence and similar counterproductive activities. Flying cars, deep sea habitats, space habitats, clean energy, hair style robots, fully coordinated jam-free personal traffic.
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astazangasta将近 9 年前
By &#x27;nanorobot&#x27; they mean bacteria.<p>&gt;We show that when MC-1 cells bearing covalently bound drug-containing nanoliposomes were injected near the tumour in severe combined immunodeficient beige mice and magnetically guided, up to 55% of MC-1 cells penetrated into hypoxic regions of HCT116 colorectal xenografts. Approximately 70 drug-loaded nanoliposomes were attached to each MC-1 cell. Our results suggest that harnessing swarms of microorganisms exhibiting magneto-aerotactic behaviour can significantly improve the therapeutic index of various nanocarriers in tumour hypoxic regions.<p>So they load these little guys up with drug and use magnets to guide them into the tumor, which kind of works in SCID mice, although you&#x27;ll note they make no claims about ability to actually kill or shrink tumors.<p>This news piece is awful, incidentally, but what else is new.
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yomly将近 9 年前
This is pretty cool research, from what I can recall hypoxic tissue is hard to treat for three reasons:<p>1. It is hard to detect 2. Hypoxic tissue is hard to access as there is little blood supply 3. Hypoxic tissue is hard and physically robust<p>So according to this release, the work done here should help to address the issues of hypoxic tissue.<p>Is anyone with deeper subject knowledge able to discuss the viability of this research: how much is hype? Are there any risks or weaknesses to this method? How commercially viable is it to mass produce this?
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Gatsky将近 9 年前
I wish these articles wouldn&#x27;t turn up here. Although this sounds cool, the chance of having an impact on actual patient care is miniscule. This is a very complcated delivery system at the end of the day. We have enough trouble giving one drug and managing toxicity successfully, let alone this controlled nano infection cocktail. Also hypoxia isn&#x27;t as tumour specific as you think, off target toxicity is a problem.<p>I don&#x27;t think anyone will be cured by this and it will no doubt cost an absolute fortune.
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hashkb将近 9 年前
This is the cancer treatment of my childhood dreams.
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amenghra将近 9 年前
Science catching up with sci-fi? <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Fantastic_Voyage" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Fantastic_Voyage</a>
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khoury将近 9 年前
Interesting comments regarding this on reddit:<p><a href="https:&#x2F;&#x2F;www.reddit.com&#x2F;r&#x2F;Futurology&#x2F;comments&#x2F;4xz4nv&#x2F;scientists_have_created_nanorobots_that_can&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.reddit.com&#x2F;r&#x2F;Futurology&#x2F;comments&#x2F;4xz4nv&#x2F;scientis...</a>
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CommanderData将近 9 年前
Haven&#x27;t we already had this for a long time? Targeted drug delivery using Nano technology? A lesser complicated version and less of the sci fi but the technology has been here and proven for a long time with some FDA approved drugs already. Most of the drugs are still in trial but targeted drug delivery looks promising.
uklenny将近 9 年前
There&#x27;s an interesting Tedex with a similar outcome but different nanobot cancer approach - <a href="http:&#x2F;&#x2F;www.ted.com&#x2F;talks&#x2F;paula_hammond_a_new_superweapon_in_the_fight_against_cancer?language=en" rel="nofollow">http:&#x2F;&#x2F;www.ted.com&#x2F;talks&#x2F;paula_hammond_a_new_superweapon_in_...</a>
wuliwong将近 9 年前
Anybody know when&#x2F;if this type of treatment could be used? Any idea of the increase in the effectiveness of cancer treatments using this technology? I read the article and skimmed the paper but didn&#x27;t get an idea of whether or not this technology is on a clear path to being a medical option for cancer patients.
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Aaronontheweb将近 9 年前
I remember reading Prey by Michael Crichton as a teenager and wondering if the nanobots he described there could be used to &quot;eat&quot; a tumor, like leaf-cutter ants gradually moving bits of material in a pipeline from one place to another. Glad to see that kind of idea realized in my lifetime.
scottlocklin将近 9 年前
I love how they&#x27;re calling bacteria &quot;nanorobots.&quot; Why not call them bacteria?
zubairq将近 9 年前
Is this real? I hope so