Going to potentially be controversial, but we need (might be a strong word here) genetic manipulation with strong ethical and humanist values attached to it (and a lot more knowledge).<p>If we are to deny natural selection its role, then we might want to still prevent people from passing on genes which effectively handicap them when they don't have access to certain facilities and technology. Prevention in this case is not eugenics, but gene manipulation/therapy.<p>Having said this, what we most certainly don't want is genetic standardisation (good path for extinction) and even the manipulation of genes, that seem to cause "problems" (today's problems might be tomorrow's cure), needs a deep understanding of implications, which at the moment we probably don't have.<p>P.S.: Hold the similar view regarding GMO in food.