From the clustering page of the Wiki:<p>"The pymq cluster is not designed to survive a master crash. If the master is to crash, all bets are off. However, clients that are already connected to the individual nodes can continue to operate normally. It's just that automatic failover and queue discovery won't work (which is basically what the master does)."<p>This is not fail-safe, unlike most enterprise messaging systems. Though you could stick the master on a VMware cluster with FT enabled and survive hardware failures, there is nothing preventing data loss from software or networking failures.