Like almost all nutritional studies, the evidence here is circumstantial and should be read with significant skepticism. Stephen Pauker, a professor of medicine at Tufts University and a pioneer in the field of clinical decision making, says, “Epidemiologic studies, like diagnostic tests, are probabilistic statements.” They don’t tell us what the truth is, he says, but they allow both physicians and patients to “estimate the truth” so they can make informed decisions.' (Excerpt from Do We Really Know What Makes Us Healthy by Gary Taubes <a href="http://www.nytimes.com/2007/09/16/magazine/16epidemiology-t.html" rel="nofollow">http://www.nytimes.com/2007/09/16/magazine/16epidemiology-t....</a>)<p>If you look at the larger body of evidence beyond this study, there are major reasons why institutional wisdom continues to advocate for the consumption of mono and polyunsaturated fats over saturated fat. For example, a larger 2016 cohort study of 115,000+ participants concluded high dietary intakes of saturated fat are associated with an increased risk of coronary heart disease (<a href="http://www.bmj.com/content/355/bmj.i5796" rel="nofollow">http://www.bmj.com/content/355/bmj.i5796</a>).<p>Eating healthier is all about what categories of food replace current calories. If similar studies continue to show vegetable oil consumption is not protective against heart disease, it will probably make more sense to advocate replacing vegetable oil calories with fatty nuts and avocados that are much more nutritiously dense than oils (my preference for where to get fats). To jump to the conclusion we should all eat more butter based on this one study of n=9,423, however, is bad logic.