Slightly off-topic.<p>The journal article is tagged with "nootropic". Modafinil is not a nootropic, but a smart drug. There is a subtle but important difference between the two. Both types of drugs enhance your cognitive performance, but a nootropic <i>must be</i> neuroprotective. Piracetam, the first nootropic synthesized in 1964 is used nowadays to treat cognitive decline [1]<p>I am not saying that modafinil will fry your brain, but definitively it is not designed to protect it.<p>In my personal experience, Modafinil works pretty well in <i>low</i> doses. 25mg-50mg every 2-3 days lifts my mood and increase my work output significantly. The recommended dosage (200mg) is a crash and burn for me.<p>[1] <a href="https://www.ncbi.nlm.nih.gov/pubmed/16007238" rel="nofollow">https://www.ncbi.nlm.nih.gov/pubmed/16007238</a>