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A community on the front lines of the opioid epidemic

56 点作者 iamjeff大约 8 年前

10 条评论

alasdair_大约 8 年前
My daughter died from a fentanyl overdose a couple of months ago.<p>Like many of the people on this site, I am a software engineer working for a top-tier tech firm in SF. Money isn&#x27;t a serious problem in our lives.<p>Total time from &quot;maybe our daughter is doing drugs?&quot; to death was less than three months. We sent her to rehab in that time because she was abusing cocaine and asked to go. I am not some ignorant parent - I&#x27;ve tried plenty of things and k ow the signs well.<p>Please, if you have kids, tell them about fentanyl. It is SO much more potent than heroin and can kill on the first dose. She went to a party, someone offered her some &quot;coke&quot;, she snorted some and she died soon after. Turns out the coke was fentanyl or at least had some in it.<p>The autopsy of my daughter showed that there were no injection marks. She had a career and in no way fit the stereotype of an addict. One day she existed, the next she did not.<p>I am neither pro nor ani drug. I don&#x27;t care about that. All i care about is telling people the story of my daughter. Fentanyl is so much more potent than heroin and it is sweeping the entire nation. If you have kids, please tell them tbat it exists and that people are selling it right now claiming its something different.
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touchofevil大约 8 年前
It seems like the real problem causing the overdoses is that fentanyl and carfentinal are getting mixed into the heroin. At the minimum, the US should provide a program where heroin addicts can get heroin from government clinics, which is what they offer in the Netherlands[1] where addicts can get heroin three times a day and apparently rarely overdose presumably because the heroin is pure. But at this point, I&#x27;d rather see most drugs legalized and the tax money poured into addiction recovery programs, government clinics for supervised drug use, and drug use prevention.<p>[1] <a href="https:&#x2F;&#x2F;news.vice.com&#x2F;article&#x2F;only-in-the-netherlands-do-addicts-complain-about-free-government-heroin" rel="nofollow">https:&#x2F;&#x2F;news.vice.com&#x2F;article&#x2F;only-in-the-netherlands-do-add...</a>
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wallace_f大约 8 年前
Meanwhile yearly marijuana overdoses stay at a constant zero every year, while enforcement of marijuana prohibition kills untold numbers of convincingly innocent people.
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gragas大约 8 年前
So what can be done? I usually update my theory about the situation when I read new articles, but now I&#x27;m really at a loss. I&#x27;d love to help these people, but I can&#x27;t see a fool-proof solution.<p>Some questions come to mind:<p>- Is it the role of the government to keep people safe from themselves? If so, how?<p>- Would harsher drug laws make things better or worse?<p>- How big of a role does purported economic opportunity have to do with drug abuse? My theory used to be that structural unemployment was the root of this epidemic; those born into the quickly receding middle class---those who relied on low-knowledge&#x2F;low-skill jobs for a modest living---are hit the hardest since they did not anticipate such a shortage of low-skill jobs.<p>- What does religion have to do with this?<p>- What does culture have to do with this?<p>- Are members of the military more or less affected by opiod drug abuse?<p>- Does providing safe places to take drugs alleviate the problem, or does it make it worse?
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mirimir大约 8 年前
So what would it cost to distribute safe heroin?<p>I mean, restricting availability of Oxycontin etc clearly hasn&#x27;t worked.<p>Edit: My point is that the Drug War is immoral.
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gm-conspiracy大约 8 年前
From August, 2016.
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goldenkey大约 8 年前
The problem isn&#x27;t opiates. It&#x27;s larger doses than necessary combined with synthetic drugs that are much more powerful than the natural poppy alkaloids.<p>Quick rundown: The poppy plant has two main alkaloids that make up the majority of its analgesic activity: codeine and morphine. Codeine works following being broken down by the liver into morphine. It&#x27;s essentially the same drug but requires larger doses due to the inefficient pathway.<p>I have had a chronic pain condition for many years now and take 30mg morphine sulfate tablets twice daily. Instant release taken often works far better than extended release drugs because the total dose is much less, which keeps tolerance levels low, thereby lower dependence.<p>Oxycodone is 1.5 to 2x as strong as morphine. [1]<p>Oxymorphone is 7-8x times as strong as morphine. [1]<p>Fentanyl is 50-100x times as strong as morphine. [1]<p>Of course this is referring to gram for gram, and these substances do have different molecular weights. But even so, the potency has much to do with bonding length between the drug and the body&#x27;s receptors. Bonding length is correlated with bonding strength, also correlated with addictive qualities.<p>For low to moderate pain, Tramadol[2] is the best analgestic. For moderate to severe pain, Tapentadol[3] (Nucynta) is by far, the most therapeutic and least addictive. I used to take it until I lost my insurance. Unfortunately it costs $1500 a bottle. It&#x27;s a newer drug. The same company Depomed that created Tramadol kept going and made a better and stronger version. Having tried gabapentin, muscle relaxers, all kinds of stuff, pretty much everything out there, I will say, Tapentadol is really an amazing drug. It&#x27;s unfortunate its so expensive and not covered by many insurances though.<p>So in summary, if a person has the insurance, the doctor should prescribe them Tapentadol or Tramadol. As a last resort, prescribe Codeine and&#x2F;or Morphine. Not these crazy synthetics with ridiculous addiction profiles and bonding strengths.<p>Hope this helps anyone who ever has a pain condition.<p>[1] <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Equianalgesic" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Equianalgesic</a><p>[2] <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Tramadol" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Tramadol</a><p>[3] <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Tapentadol" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Tapentadol</a>
michaelhoney大约 8 年前
Serious question: would it not be better to make opioid painkillers available again, rather that have people substitute with heroin or worse?
addict_gt大约 8 年前
I&#x27;m reluctantly commenting, throwaway account. I had spent an hour writing this huge note, but don&#x27;t think it was constructive. Check out the reddit description of opiates and heroin, the youtube spoken word video will help non-addicts understand the power of these drugs and the control they have over your life and your brain chemistry and how easy it is to become dependent.<p>I am an addict. I have been all of my life, and will be until the day I die (hopefully at an old age and happy).<p>I&#x27;m also business owner, young and I would say very successful compared to others in my age group.<p>Ironically, I actually credit Oxy for getting sober from alcohol (coming on 3 years), and I&#x27;ve been sober from cocaine for probably around 3.5 years (don&#x27;t remember, very blurry).<p>However I&#x27;m currently dependent on opiate pills and I feel very lucky that I can afford my addiction, at least for now.<p>I&#x27;m afraid to get sober. I&#x27;m afraid to tell the truth to the ones I love who supported and congratulated me on getting sober from alcohol and cocaine.<p>Instead of telly a long story, I wanted to offer some ideas to this community, from the perspective of an addict and entrepreneur, a few of these could even be successful startups that save lives:<p>1) doctors need to stop prescribing. I am very open with my Doctor, it is written on the front page of the screen that shows my health record: previously cocaine dependent, alcoholic. Yet when I went in for a bad burn, they prescribed Percocet. I went to the doctors seeking some numbing cream and to ensure I didn&#x27;t get an infection. But I got pills, and I&#x27;m an addict. I KNEW 100% I would become addicted. It didn&#x27;t happen over night of course, but here I am. Replacement therapy is called liquid handcuffs for a reason: methadone is dangerous and deadly, Sub withdrawal I hear is worse than oxy&#x2F;heroin withdrawal. I would love to see an experiment long term between traditional replacement therapy, compared to actually supplying addicts with pure drugs.<p>2) make a reliable and widely available and free test kit to detect Fent and other deadly synthetic and powerful opiates.<p>3) make a cheap wearable fitbit like device. It will detect slowed&#x2F;stopped breathing and alert either authorities or maybe an app that has listed contacts who are trained and have access to naloxone, like a rape or danger alert sent to your designated contacts and if no response 911. It would have to have little monetary value so it&#x27;s not sold, but maybe could help save some lives.<p>4) make an implant that can detect slow breathing&#x2F;overdose and administer naloxone during an overdose internally. Like a diabetes monitor&#x2F;pump.<p>5) sue Purdue and change our countries addiction to prescription pain killers. To me this is the big tobacco of our time. They spent millions and millions advertising and buying doctors telling them this is a non-addictive 12 hour pain reliever. Pain in the past was rarely medicated. Purdue changed this and made billions. The truth is Percocet&#x2F;Oxy usually lasts only 6-8 hours, maybe 10 if you&#x27;re lucky. Each individual is unique. Purdue advertised 12 hours non-addictive and that&#x27;s how doctors prescribed. so when the pain comes back before 12 hours or you start getting sick you take the next pill. And you use your entire script before the next refill. They MUST have known this. Profiting on addiction is shameful. Marketing a product to purposefully create addicts to sell more pills is criminal an I hope that somebody can leak or a prosecutor can make this case and bring some justice, and badly needed funding to aid in recovery, research, and alternative replacement options.
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revmoo大约 8 年前
Gonna get worse once they ban kratom. Brace yourselves.