What are the ethics of trying this in terminal patients? Surely I’d give it punt and hope for the best should I ever have brain cancer and if not we’d all learn something right? Why is it that we don’t treat terminally ill patients the same way we treat DOA car accident victims and aim to give them the opportunity to contribute?
This would seem to be the source: <a href="http://jem.rupress.org/content/early/2017/09/05/jem.20171093" rel="nofollow">http://jem.rupress.org/content/early/2017/09/05/jem.20171093</a>
I've got a friend with stage four glioblastoma. I'd really love to be able to sign him up for one of these trials. Unfortunately, the article says human trials are 18 months away, and I doubt he will live that long.
I'd love for somebody to explain how you get a group of brain tumor-bearing mice. Can one somehow prompt glioblastoma to occur in some meaningful percentage of mice? I scanned the paper but found nothing.