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Chainer Chemistry: A Library for Deep Learning in Biology and Chemistry

59 点作者 wei_jok超过 7 年前

4 条评论

lilleswing超过 7 年前
Really cool stuff here, a lot along the same lines of what we have been trying to do with DeepChem and MoleculeNet.<p><a href="https:&#x2F;&#x2F;deepchem.io&#x2F;" rel="nofollow">https:&#x2F;&#x2F;deepchem.io&#x2F;</a><p><a href="https:&#x2F;&#x2F;github.com&#x2F;deepchem&#x2F;deepchem" rel="nofollow">https:&#x2F;&#x2F;github.com&#x2F;deepchem&#x2F;deepchem</a><p><a href="http:&#x2F;&#x2F;moleculenet.ai&#x2F;" rel="nofollow">http:&#x2F;&#x2F;moleculenet.ai&#x2F;</a><p>We seem to be a little further along and stable than this repo. We are also based on Tensorflow instead of raw cuda which means users can play around with the networks more easily.
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brilee超过 7 年前
Excellent. I&#x27;d been wanting to implement something like this but these guys beat me to the punch.<p>Most existing research on NNs in chemistry uses the SMILES string representation and feeds it into a recurrent neural network. The problem with SMILES in my opinion, is that SMILES is not unique, and there are a gazillion ways to represent the same molecule. Thus, the RNN is probably overfitting to the quirks of the SMILES serialization algorithm used by the US Patent Office and&#x2F;or ChemDraw and&#x2F;or whatever program was used to generate the library of molecules.<p>Convolutional graph networks are the obviously correct way to handle molecules.
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Pulcinella超过 7 年前
This seems like the development of an artificial chemical intuition[0][1] except since its a computer it can intuit concrete numbers much more comfortably than humans can. I do wonder how its accuracy compares to just running the DFT calculations.<p>[0]wavefunction.fieldofscience.com&#x2F;2016&#x2F;09&#x2F;what-is-chemical-intuition.html<p>[1]<a href="https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=12624036" rel="nofollow">https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=12624036</a>
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corochann超过 7 年前
Links of Chainer Chemistry<p>- blog: <a href="https:&#x2F;&#x2F;preferredresearch.jp&#x2F;2017&#x2F;12&#x2F;18&#x2F;chainer-chemistry-beta-release&#x2F;" rel="nofollow">https:&#x2F;&#x2F;preferredresearch.jp&#x2F;2017&#x2F;12&#x2F;18&#x2F;chainer-chemistry-be...</a><p>- github: <a href="https:&#x2F;&#x2F;github.com&#x2F;pfnet-research&#x2F;chainer-chemistry" rel="nofollow">https:&#x2F;&#x2F;github.com&#x2F;pfnet-research&#x2F;chainer-chemistry</a><p>- document: <a href="http:&#x2F;&#x2F;chainer-chemistry.readthedocs.io&#x2F;en&#x2F;latest&#x2F;index.html" rel="nofollow">http:&#x2F;&#x2F;chainer-chemistry.readthedocs.io&#x2F;en&#x2F;latest&#x2F;index.html</a>