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How Genetics Is Changing Our Understanding of ‘Race’

56 点作者 marchenko大约 7 年前

6 条评论

tptacek大约 7 年前
This piece makes an important argument, but if you look around Twitter for the academic reaction to it, it is not unanimously positive. In particular, you can find neurogeneticists taking issue with a thesis built from &quot;there has been enough time for natural selection in human populations&quot; <i>and</i> &quot;genes probably play a role in intelligence&quot;; the story is apparently not that simple given what we apparently know about genes and intelligence (polygenic, impact multiple other things besides intelligence).<p>So while it may be the case that &quot;race is purely a social construct&quot; is an untenable and unproductive position, it does not necessarily follow that a solid case for &quot;achievement and behavior is strongly genetic&quot; has been made.<p>Since intelligence and genetics is the third rail of population genetic studies, isn&#x27;t the author&#x27;s specialty, and isn&#x27;t at all clear, it&#x27;s a little confusing as to why he went out on this limb. Pinker sure is happy about it though.<p>A good next read:<p><a href="https:&#x2F;&#x2F;gcbias.org&#x2F;2018&#x2F;03&#x2F;14&#x2F;polygenic-scores-and-tea-drinking&#x2F;" rel="nofollow">https:&#x2F;&#x2F;gcbias.org&#x2F;2018&#x2F;03&#x2F;14&#x2F;polygenic-scores-and-tea-drink...</a>
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Chardok大约 7 年前
This concept of a &quot;race&quot;, in terms of genetics, makes sense for classification purposes, just like all taxonomical classifications of living things.<p>The difference here, is that people are taking this genetic concept of &quot;race&quot; and trying to prove their racist points, which always misses the point entirely. It would be a non-issue if the word &quot;race&quot; wasn&#x27;t so politically charged.<p>Quick edit for 2 easy examples: People with African descent are more likely to have sickle cell anemia, due to the resistance the gene provides against malaria.<p>People with European descent are more likely to have cystic fibrosis, due to resistance it provided from cholera and typhoid.
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cgiles大约 7 年前
I have no idea whether the overall pendulum is swinging back from &quot;race is a purely social construct&quot;. I hope so, because it has always seemed absurd to me, for the very reasons the author cites, just as absurd as the idea that race is a hard determinant of anything.<p>But what I can say is that in molecular biology, working scientists have completely ignored this politically charged debate and continued to use the concept this whole time. In one example I am directly familiar with, researchers have continued to use and stratify genome-wide association studies by self-reported race&#x2F;ethnicity in the search for variants causal for lupus. This is important not only because as with many diseases, there is a difference in likelihood of getting the disease between &quot;races&quot; not attributable to lifestyle, but also because it is entirely possible, even probable, that the mechanisms causing the disease are somewhat different between ethnicities.<p>Actually, therefore, the understanding that there are real differences between &quot;races&quot; in the context of disease is actually helpful for the smaller groups because it means that special attention is paid to the etiology of their disease apart from the general etiology. In the same way that, for many years, most biology research was done on males and it was just assumed that the findings would always apply to females. That was incorrect, and now studies are done to determine gender differences in treatment and disease etiology.<p>IMO this whole debate has dragged on as long as it has because too many in the public are seemingly incapable -- or unwilling -- to understand basic concepts about population means and variances, and in particular that in a situation like this where population means are very real but usually small, and the variance is high, knowing what &quot;race&quot; you are <i>usually</i> conveys little information about some other attribute of interest. Usually, but not always, as is particularly the case with many diseases.<p>I have grown particularly tired of the argument that, because a taxonomy, like any clustering, is fuzzy and the number of clusters is somewhat arbitrary, the whole thing conveys no useful information. It is patently false.
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darepublic大约 7 年前
Reading between the lines; using genetics to justify racism against group X is dreadfully wrong, but let&#x27;s not close the door on our ability to use genetics to justify racism against group Y.
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apk-d大约 7 年前
There is no race, it&#x27;s all just brains doing overactive classification. I wish that we got over this as a species already.
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factsaresacred大约 7 年前
The idea that race is a social construct is simply dumb.<p>Race: Genetic characteristics common to humans with a shared geographic origin, and that differ from humans from other geographic origins, sometimes distinguishable by appearance.<p>If our collective memory was wiped today, tomorrow we would distinguish humans by what we call &#x27;races&#x27;. But it would require science to clarify what distinguishes a race at the genetic level (physical differences being a decent proxy but often wrong and clearly primitive) and to map the distinct differences between each race.<p>Why is this controversial?
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