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Secret to longevity may lie in the microbiome and the gut

154 点作者 Mrtierne将近 7 年前

8 条评论

gojomo将近 7 年前
I&#x27;m a believer in the importance of the microbiome, but this study seems fishy:<p>* the authors have already started a company and pursued a patent on their ayurvedic-derived formulation<p>* the figure 1(a) in their paper (<a href="https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;s41598-018-25382-z#Fig1" rel="nofollow">https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;s41598-018-25382-z#Fig1</a>) doesn&#x27;t show a big difference from plain probiotics to their formulation, but does show some oddities in the Y-axis where, for the control group, there were clearly exactly just 10 flies&#x27; mortality measured (integer steps down), but apparently many, many more for other cases scaled to the 0-10 axis.<p>* it&#x27;s unclear if the treatments&#x2F;evaluations where blinded – the word &#x27;blind&#x27; is not found in the Nature article<p>* the 1st comment on the Nature article wonders: &quot;the control flies didn&#x27;t live to their normal expected age or even close. What gives?&quot;<p>(Perhaps the flies that lived longer just had more food in total?)
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avip将近 7 年前
I’m working in proximate space. Every research paper about nutrition in general and gut bacteria specifically should be assumed shit science.
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unicornporn将近 7 年前
In a few years we might look back at this period and think: oh, it was at the time when we thought gut bacteria was the solution to every health problem known to mankind.<p>Remember when it was vitamin D?
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deepsun将近 7 年前
Advertisement of a herbal supplement.
gweinberg将近 7 年前
I think there&#x27;s been very little evolutionary pressure to increase lifespan in creatures like fruit flies since despite their short lifespan few of them die from age related causes. I would assume it&#x27;s pretty easy to increase the lifetime of short-lived creatures in a protected environment, and pretty unlikely that the methods which accomplish this would also extend the lives of long-lived creatures.
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ogennadi将近 7 年前
&gt; Scientists fed fruit flies with a combination of probiotics and an herbal supplement called Triphala that was able to prolong the flies&#x27; longevity by 60 percent and protect them against chronic diseases associated with aging.<p>For comparison, dietary restriction increases longevity in rats and mice by up to 45%, but this may only be in lab animals<p><a href="https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC3299887&#x2F;" rel="nofollow">https:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC3299887&#x2F;</a>
Latteland将近 7 年前
Wait, it&#x27;s an internet law that every article that asks if &quot;&lt;something&gt; may be the solution to &lt;some problem&gt;&quot; it is never the solution.
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baxtr将近 7 年前
The topic microbime is definitely on the rise right now. It will soon reach mainstream media.<p><a href="https:&#x2F;&#x2F;trends.google.com&#x2F;trends&#x2F;explore?date=today%205-y&amp;geo=US&amp;q=Microbiome" rel="nofollow">https:&#x2F;&#x2F;trends.google.com&#x2F;trends&#x2F;explore?date=today%205-y&amp;ge...</a>