First, smaller is easier for meeting people and actually have worthwhile conversations (jumping into a large group of well-known people at a conference afterparty isn't going to create any new friends, normally).<p>Find any local meetups first and go there. I went to my first networking conference, SXSW a few years ago, and met one person, who intro-ed me to three others. Contact continued when we were all on the same flight home, and I offered to drive them from the airport. These three then intro-ed me to new people, who then intro-ed me to more... this is the best way, imho, to create honest connections that don't disappear once you leave a party.<p>Also, Twitter is a pretty easy way to continue connections after you've met someone briefly.<p>As for approaching people to initiate conversations, just do it. Jump in, say hi, start listening, and speak up when you have the chance. But if you want to actually add someone to your "network", find a way to follow up after so they remember who you are.