I sometimes see people ask about translating a language like Python to Common Lisp (or another language that can be compiled) as a kind of optimization.<p>The problem, in general, isn't that Python and languages like it don't have a compiler, it's that the semantics of the language are hostile to good performance by traditional means of compilation. To do what the programmer requests requires doing things at runtime that are hard to make fast. That's why things like tracing JITs are being used for things like JavaScript.<p>The speedup you get from actually compiling Python programs is because the CPython interpreter is pretty awful, not because compilation is a magic solution to performance problems. The IronPython guy gave a nice explanation of this at OOPSLA 2007's Dynamic Languages Symposium - maybe things have changed in CPython since then.